Biosynthetic Pathways

MODPROPEP

MODPROPEP is a structure based program for analysis and prediction of substrates for protein kinases and MHC proteins

SBSPKS

Structure based sequence analysis of polyketide synthases. (Contributed to Structural Modules)

SBSPKSv2: structure-based sequence analysis of polyketide synthases and non-ribosomal peptide synthetases

Genome guided discovery of novel natural products has been a promising approach for identification of new bioactive compounds. SBSPKS web-server has been a valuable resource for analysis of polyketide synthase (PKS) and non-ribosomal peptide …

EFICAz2. 5: application of a high-precision enzyme function predictor to 396 proteomes

**Summary**: High-quality enzyme function annotation is essential for understanding the biochemistry, metabolism and disease processes of organisms. Previously, we developed a multi-component high-precision enzyme function predictor, EFICAz2 (enzyme …

SBSPKS: structure based sequence analysis of polyketide synthases

Polyketide synthases (PKSs) catalyze biosynthesis of a diverse family of pharmaceutically important secondary metabolites. Bioinformatics analysis of sequence and structural features of PKS proteins plays a crucial role in discovery of new natural …

Identification of substrates for Ser/Thr kinases using residue-based statistical pair potentials

**Motivation**: In silico methods are being widely used for identifying substrates for various kinases and deciphering cell signaling networks. However, most of the available phosphorylation site prediction methods use motifs or profiles derived from …

MODPROPEP: a program for knowledge-based modeling of protein–peptide complexes

MODPROPEP is a web server for knowledge-based modeling of protein–peptide complexes, specifically peptides in complex with major histocompatibility complex (MHC) proteins and kinases. The available crystal structures of protein–peptide complexes in …